产品货号：
Z36976
中文名称：
IKZF1抗体
英文名称：
Anti-IKZF1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IKZF1 Antibody |
| 指标别名 | DNA binding protein Ikaros;hIk 1;Hs.54452;IK1;IKAROS;IKZF1;LYF1;PRO0758;ZNFN1A1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | IKZF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Ikaros Transcription regulator of hematopoietic cell differentiation (PubMed:17934067).Binds gamma-satellite DNA (PubMed:17135265,PubMed:19141594).Plays a role in the development of lymphocytes,B- and T-cells. |
| 实际分子量 | 50～70KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DNA-binding protein Ikaros is a protein that in humans is encoded by the IKZF1 gene.This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling.The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system,and it functions as a regulator of lymphocyte differentiation.Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.Most isoforms share a common C-terminal domain,which contains two zinc finger motifs that are required for hetero- or homo-dimerization,and for interactions with other proteins.The isoforms,however,differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence,resulting in members with and without DNA-binding properties.Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes.The non-DNA-binding isoforms are largely found in the cytoplasm,and are thought to function as dominant-negative factors. |
| Uniprot ID | Q13422 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：IKZF1抗体，IKZF1单抗，Anti-IKZF1 Antibody